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Lots of drugs have been manufactured to cure migraines. Medications used to combat migraines fall into two main categories:
- Pain-relieving medications: Also known as acute or abortive treatment, these types of medication are used at the time of migraine attacks and are designed to stop symptoms.
- Preventive medications: these types of medication are used regularly, usually daily, to decrease the severity or frequency or migraines.
Your treatment mainly depends on the frequency and severity of your head pain, whether you have nausea and vomiting with your headaches, how disabling your headaches are, and other medical situations or conditions you have.
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Medications prescribed to relieve migraine pain functions best when taken at the first sign of an oncoming migraine- as soon as signs and symptoms of migraine starts. Medications that can be used to diagnose it include:
- Pain relievers: these over-the-counter or prescription pain relievers like: aspirin or ibuprofen (advil, motrin IB, etc.). When used too long, these might cause medication-overuse head pain, and may be stomach ulcers and bleeding in the gastrointestinal tract.
- Migraine relief drugs that combine caffeine, acetaminophen (Excedrin migraine) and aspirin may be much helpful, but commonly only against mild to moderate migraine pain.
- Triptans:It is a prescription medication like sumatriptan (imitrex, tosymaetc) and rizatriptan (maxalt) are prescription medication used for migraine because they prevent pain pathways in the brain. Taken as tablets, shots or nasal sprays, they can relieve a variety of symptoms of migraine. They might not be safe or much effective for those at risk of a stroke or heart attack.
- Opioid medications: the patients who have migraines who cannot use other migraine drugs, narcotic opioid medications, especially those that involve codeine, might help. Because they can be much addictive, these are commonly used only if no other treatments are effective.
- Anti-nausea drugs: these drugs may be helpful if your migraine with aura is accompanied by nausea and vomiting. Anti-nausea medication for instance: prochlorperazine, metoclopramide, and chlorpromazine are widely used with pain drugs.
- Dihydroergotamine (D.H.E. 45, migranal):these are available as a nasal spray or injection, these are most safe and effective when used shortly after begins of migraine symptoms for migraines that tend to last longer than 24 hours. Side effects such as: worsening of migraine related vomiting and nausea.
Medications can help prevent frequent migraines. Your doctor might recommend preventive medications if you have frequent, long-lasting or severe headaches that do not respond well to treatment.
Preventive medication is aimed at decreasing how often you get a migraine, how serious or severe the attacks are and how long they last. Options include:
- Blood pressure-lowering medications: these include beta blockers medication for instance: metoprolol tartrate (Lopressor) and propranolol (Inderal, innopran XL, others). Calcium channel blockers medication such as verapamil (tarka, verelan) may be much helpful in preventing migraines with aura.
- Antidepressants: a tricyclic antidepressant 9amitriptyline) can prevent migraines. Because of the side effects of amitriptyline, such as vomiting or nausea, sleepiness and weight gain, other antidepressants might be prescribed instead.
- Anti-seizure drugs:valproate and topiramate (Topamax) might help you have less frequent migraines, but can cause side effects such as dizziness, weight changes, nausea etc.
- Botox injections: this injections of onabotulinumtoxinA (Botox) about every six month help eradicate migraines in some patients.
- Calcitonin gene-related peptide (CGRP) monoclonal antibodies:erenumab-yahoo (amimovig), fremanezumab-vfrm (ajovy) and galcanezumab-gnlm (emgality) are newer drugs approved by the food and drug administration to treat migraines. They are given monthly by injection. The most common side effect is a reaction at the injections site.